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PSEN1

Presenilin-1 (PS-1) is a protein that in humans is encoded by the PSEN1 gene. Presenilin 1 is one of the four core proteins in presenilin complex, which mediate the regulated proteolytic events of several proteins in the cell, including gamma secretase.

PSEN1PresenilinCrenezumabEarly-onset Alzheimer's diseasePSEN2List of OMIM disorder codesFLNBCalsenilinUBQLN1NicastrinCTNND1Beta-cateninICAM5Glial fibrillary acidic proteinPKP4Chromosome 14 (human)Dilated cardiomyopathyBcl-2

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